Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 15/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007755 | 0.92 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL7009180 | 0.89 | AGTR1 (0.46) | AGTR1 | |
| SCHEMBL7012215 | 0.84 | AGTR1 (0.53) | AGTR1 | |
| SCHEMBL7013028 | 0.82 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL9044284 | 0.78 | AGTR1 (0.43) | AGTR1 | |
| SCHEMBL9044702 | 0.78 | AGTR1 (0.46) | AGTR1 | |
| SCHEMBL9044761 | 0.77 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL9194238 | 0.77 | — | — | |
| SCHEMBL7007439 | 0.77 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL9049056 | 0.77 | AGTR1 (0.45) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1327631-A2 | Fused heterocyclic compounds, their production and use as angiotensin II antagonists | Takeda Chemical Industries, Ltd. (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-0518033-B1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-5389641-A | Fused heterocyclic compounds, having angiotensin II antagonistic activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0518033-A1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |