Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444592 | 0.74 | — | — | |
| SCHEMBL697911 | 0.74 | — | — | |
| SCHEMBL8963106 | 0.71 | ACHE (0.39) | MGAMGAASIMGAM2 | |
| SCHEMBL4444589 | 0.69 | — | — | |
| SCHEMBL27393398 | 0.68 | ACHE (0.43) | MGAMGAASIMGAM2 | |
| SCHEMBL30678378 | 0.67 | KMT2A (0.45) | MGAMGAASIMGAM2 | |
| SCHEMBL11208718 | 0.65 | NAAA (0.41) | MGAMGAASIMGAM2 | |
| SCHEMBL590531 | 0.65 | EPHX1 (0.53) | MAPT | |
| SCHEMBL6971167 | 0.65 | — | — | |
| SCHEMBL29010638 | 0.64 | GAA (0.35) | POLBMAPTMGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351959-A1 | NOVEL PLEUROMUTILIN DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002030929-A1 | NOVEL PLEUROMUTILIN DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-04-18 | — | — | WO | disclosed |