Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
| ▸ | ATIC | P31939 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14535805 | 0.84 | RECQL (0.55) | GLO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3061022 | 0.79 | GLO1 (0.58) | GLO1PTGES2KDM4ESLC40A1ATIC | |
| SCHEMBL7572129 | 0.76 | GLO1 (0.60) | GLO1KDM4EATICSTAT3ACLY | |
| SCHEMBL3061242 | 0.76 | CA1 (0.73) | GLO1PTGES2ATICSTAT3ACLY | |
| SCHEMBL7571206 | 0.75 | RECQL (0.69) | GLO1PTGES2KDM4ESTAT3ACLY | |
| SCHEMBL16592703 | 0.74 | TSHR (0.65) | GLO1KDM4ESTAT3ACLYHSD11B1 | |
| SCHEMBL12485134 | 0.73 | GLO1 (0.54) | GLO1STAT3ACLYHSD11B1 | |
| SCHEMBL3060857 | 0.72 | CRBN (0.55) | GLO1PTGES2ATICSTAT3ACLY | |
| SCHEMBL13486175 | 0.71 | GLO1 (1.00) | GLO1SLC40A1 | |
| SCHEMBL30925511 | 0.71 | GLO1 (1.00) | GLO1SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673937-B1 | BICYCLIC HETEROCYCLIC SULFONAMIDE AND SULFONIC ESTER DERIVATIVES | EISAI CO LTD (JP) | 2003-11-26 | — | — | EP | claimed |