Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | ACLY | P53396 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.51 |
| ▸ | BRD1 | O95696 | 2/20 | 0.51 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.51 |
| ▸ | BRPF3 | Q9ULD4 | 2/20 | 0.51 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.51 |
| ▸ | ATIC | P31939 | 2/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28316252 | 0.83 | LMNA (0.69) | KDM4EHSD11B1CYP19A1ARBRD1 | |
| SCHEMBL7571206 | 0.83 | RECQL (0.69) | GLO1KDM4ESTAT3ACLYHSD11B1 | |
| SCHEMBL7577515 | 0.81 | SMN1; SMN2 (0.65) | GLO1 | |
| SCHEMBL7589336 | 0.81 | SLC22A12 (0.54) | GLO1STAT3ACLYCYP19A1SLC22A12 | |
| SCHEMBL12230253 | 0.80 | ATM (0.67) | KDM4ECYP19A1ARBRD1BRPF1 | |
| SCHEMBL14645850 | 0.79 | ALDH1A1 (0.65) | GLO1KDM4ESTAT3ACLYHSD11B1 | |
| SCHEMBL16592703 | 0.79 | TSHR (0.65) | GLO1KDM4ESTAT3ACLYHSD11B1 | |
| SCHEMBL7595509 | 0.78 | SLC22A12 (0.56) | GLO1ACLYHSD11B1SLC22A12ATIC | |
| SCHEMBL14645822 | 0.78 | CYP19A1 (0.75) | KDM4EHSD11B1CYP19A1ARSLC22A12 | |
| SCHEMBL7571483 | 0.78 | LMNA (0.67) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |