SCHEMBL7013464

SCHEMBL7013464

COC(=O)c1ccccc1CS(=O)(=O)NC(=O)Cc1nc(OC)cc(OC)n1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TP53 P04637 1/20 0.41
GLA P06280 1/20 0.41
MAPT P10636 1/20 0.41
LMNA P02545 1/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
MAPK8 P45983 1/20 0.39
MAPK9 P45984 1/20 0.39
MAPK10 P53779 1/20 0.39
RORC P51449 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
KDM4E B2RXH2 2/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA5A P35218 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9461802 0.84 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2TP53GLAMAPT
Bensulfuron Methyl SCHEMBL27491070 0.82 GAA (0.51) ALDH1A1SMN1; SMN2TP53GLAMAPT
Bensulfuron Methyl SCHEMBL6382944 0.82 GAA (0.51) ALDH1A1SMN1; SMN2TP53GLAMAPT
Bensulfuron Methyl SCHEMBL29368260 0.82 GAA (0.51) ALDH1A1SMN1; SMN2TP53GLAMAPT
Bensulfuron Methyl SCHEMBL55028 0.82 GAA (0.51) ALDH1A1SMN1; SMN2TP53GLAMAPT
SCHEMBL1765911 0.81 MAPT (0.47) ALDH1A1SMN1; SMN2TP53GLAMAPT
Bensulfuron Methyl SCHEMBL15524972 0.81 GAA (0.50) ALDH1A1SMN1; SMN2TP53GLAMAPT
SCHEMBL10524876 0.81 MAPT (0.48) ALDH1A1SMN1; SMN2TP53GLAMAPT
SCHEMBL8159477 0.81 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2TP53GLAMAPT
SCHEMBL10394921 0.80 MAPT (0.51) ALDH1A1SMN1; SMN2TP53GLAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2282371-A None JP disclosed
EP-0353640-B2 Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators BAYER CROPSCIENCE GMBH (DE) 2003-10-15 EP disclosed
EP-0353640-B1 Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators HOECHST SCHERING AGREVO GMBH (DE) 1995-04-12 EP disclosed
US-5186736-A Pre- and postemergence HOECHST AKTIENGESELLSCHAFT (DE) 1993-02-16 US disclosed
US-5053072-A HETEROCYCLIC N-ACYLSULFONAMIDES, AND THEIR USE AS HERBICIDES OR GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1991-10-01 US disclosed
JP-H02282371-A HETEROCYCLIC N-ACYLSULFONAMIDE, ITS PRODUCTION, AGENT INCLUDING THE SAME, AND THEIR USE AS HERBICIDE OR GROWTH REGULATOR HOECHST AG 1990-11-19 JP disclosed
EP-0353640-A2 Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators Hoechst Schering AgrEvo GmbH (DE) 1990-02-07 EP disclosed