SCHEMBL701347

SCHEMBL701347

COC(=O)C(C)=CC12CC3(C)CC(C)(CC(O)(C3)C1)C2

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.33
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL701252 0.81 DPP4 (0.36) DPP4
SCHEMBL701243 0.78 DPP4 (0.33) DPP4
SCHEMBL4085810 0.76 TSHR (0.30) TSHRHSD17B10
SCHEMBL701269 0.73
SCHEMBL701445 0.73 PKM (0.36) DPP4TSHR
SCHEMBL5935971 0.71 PKM (0.30)
SCHEMBL4092697 0.69
SCHEMBL4093352 0.69 TSHR (0.36) TSHRHSD17B10
SCHEMBL4097335 0.68
SCHEMBL2888060 0.67 TSHR (0.40) DPP4TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124314-B2 Radiation-sensitive composition JSR CORPORATION (JP) 2012-02-28 US disclosed
US-20100221664-A1 RADIATION-SENSITIVE COMPOSITION JSR CORPORATION (JP) 2010-09-02 US disclosed