Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019267 | 0.92 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL8469153 | 0.81 | CRHR1 (0.31) | CRHR1 | |
| SCHEMBL7014696 | 0.80 | CRHR1 (0.35) | L3MBTL1CRHR1 | |
| SCHEMBL7009568 | 0.80 | L3MBTL1 (0.33) | L3MBTL1CRHR1 | |
| SCHEMBL7016559 | 0.80 | CRHR1 (0.35) | L3MBTL1CRHR1 | |
| SCHEMBL7694374 | 0.77 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL7013733 | 0.75 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL809834 | 0.74 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL7017723 | 0.74 | CRHR1 (0.37) | CRHR1 | |
| SCHEMBL7013557 | 0.71 | CRHR1 (0.39) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920429-B1 | SUBSTITUTED PYRIDO- OR PYRIMIDO-CONTAINING 6,6- OR 6,7-BICYCLIC DERIVATIVES | PFIZER (US) | 2003-02-19 | — | — | EP | disclosed |
| US-6492520-B1 | COMPOUNDS (I) ARE CORTICOTROPIN RELEASING FACTOR (HORMONE) CRF (CRH) ANTAGONISTS. | PFIZER INC | 2002-12-10 | — | — | US | disclosed |