Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 9/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 8/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021424 | 0.84 | MTNR1A (0.48) | EPHX2SMN1; SMN2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL7018275 | 0.79 | ERCC1 (0.45) | HPGDNPC1RAB9AALDH1A1USP2 | |
| SCHEMBL7198759 | 0.78 | MTNR1A (0.52) | EPHX2SMN1; SMN2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL7017975 | 0.75 | MTNR1A (0.57) | SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL6075864 | 0.73 | SPR (0.41) | HPGDNPC1PKMRAB9AMTNR1A | |
| SCHEMBL7015840 | 0.67 | MTNR1A (0.71) | MTNR1AMTNR1B | |
| SCHEMBL7017973 | 0.65 | CXCR2 (0.39) | — | |
| SCHEMBL6076107 | 0.65 | KMT2A (0.32) | HPGDPKMALDH1A1USP2ERCC1 | |
| SCHEMBL7201899 | 0.65 | MTNR1A (0.56) | SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL5520753 | 0.64 | HTR2C (0.70) | HPGDEPHX2SMN1; SMN2ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |