Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 13/20 | 0.36 |
| ▸ | ACACA | Q13085 | 5/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017975 | 0.75 | MTNR1A (0.57) | HSD11B1 | |
| SCHEMBL1391166 | 0.72 | HSD11B1 (0.60) | CXCR2HSD11B1ACACBACACACXCR1 | |
| SCHEMBL1390942 | 0.69 | RORC (0.42) | CXCR2HSD11B1CXCR1DRD2DRD3 | |
| SCHEMBL1390598 | 0.69 | RORC (0.42) | CXCR2HSD11B1CXCR1DRD2DRD3 | |
| SCHEMBL1390601 | 0.69 | RORC (0.42) | CXCR2HSD11B1CXCR1DRD2DRD3 | |
| SCHEMBL1390545 | 0.69 | RORC (0.42) | CXCR2HSD11B1CXCR1DRD2DRD3 | |
| SCHEMBL7921681 | 0.69 | RORC (0.42) | CXCR2HSD11B1CXCR1DRD2DRD3 | |
| SCHEMBL1390922 | 0.69 | RORC (0.42) | CXCR2HSD11B1CXCR1DRD2DRD3 | |
| SCHEMBL1390540 | 0.69 | RORC (0.42) | CXCR2HSD11B1CXCR1DRD2DRD3 | |
| SCHEMBL18417128 | 0.67 | DRD3 (0.52) | HSD11B1CHRM1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |