Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 2/20 | 0.33 |
| ▸ | SKP1 | P63208 | 2/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492161 | 0.85 | OPRM1 (0.41) | OPRM1OPRD1OGFRL1MAPTBACE1 | |
| SCHEMBL22749636 | 0.76 | GPR119 (0.42) | MAPTMEN1KMT2ATP53 | |
| SCHEMBL29796145 | 0.76 | GPR119 (0.42) | MAPTMEN1KMT2ATP53 | |
| SCHEMBL5544207 | 0.68 | NPY2R (0.42) | MAPTMEN1KMT2A | |
| SCHEMBL22749600 | 0.66 | MAPT (0.42) | MAPTMEN1KMT2ATP53 | |
| SCHEMBL31211053 | 0.65 | TP53 (0.41) | MAPTTP53 | |
| SCHEMBL22723391 | 0.64 | GPR119 (0.44) | MAPTMEN1KMT2A | |
| SCHEMBL24963657 | 0.64 | GPR119 (0.44) | OPRM1OPRD1OGFRL1MAPTCKS1B | |
| SCHEMBL34471392 | 0.64 | STS (0.37) | OPRM1OPRD1OGFRL1MAPTMEN1 | |
| SCHEMBL31210361 | 0.64 | LMNA (0.45) | OPRM1OPRD1OGFRL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1342717-A1 | BENZIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-09-10 | — | — | EP | disclosed |