Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 18/20 | 0.44 |
| ▸ | MMP12 | P39900 | 5/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 11/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943704 | 0.83 | MMP13 (0.54) | MMP1MMP13MMP12FPR2PROKR1 | |
| SCHEMBL940675 | 0.81 | MMP13 (0.44) | MMP1MMP13MMP12FPR2PROKR1 | |
| SCHEMBL941666 | 0.81 | MMP13 (0.55) | MMP1MMP13MMP12FPR2PROKR1 | |
| SCHEMBL942210 | 0.81 | MMP13 (0.49) | MMP1MMP13MMP12FPR2PROKR1 | |
| SCHEMBL940856 | 0.81 | MMP13 (0.53) | MMP1MMP13MMP12FPR2PROKR1 | |
| Trifluoroacetic Acid SCHEMBL942607 | 0.80 | MMP13 (0.44) | MMP1MMP13MMP12FPR2PROKR1 | |
| SCHEMBL940710 | 0.80 | MMP13 (0.49) | MMP1MMP13MMP12FPR2PROKR1 | |
| SCHEMBL941944 | 0.79 | MMP13 (0.49) | MMP1MMP13MMP12FPR2PROKR1 | |
| SCHEMBL7013882 | 0.79 | MMP1 (0.46) | MMP1MMP13MMP12FPR2PROKR1 | |
| SCHEMBL940657 | 0.79 | MMP13 (0.50) | MMP1MMP13MMP12FPR2PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370536-A1 | METALLOPROTEINASE INHIBITORS | AstraZeneca AB (SE) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002074750-A1 | METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | WO | disclosed |