Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | VNN1 | O95497 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163688 | 0.88 | CHRM2 (0.71) | CHRM2ALDH1A1LMNAMCHR1SMN1; SMN2 | |
| SCHEMBL2263025 | 0.77 | CHRM2 (0.64) | CHRM2ALDH1A1LMNAMCHR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3668846 | 0.77 | MEN1 (0.65) | CHRM2LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL19434652 | 0.77 | CHRM2 (0.91) | CHRM2ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL11672256 | 0.77 | CHRM2 (0.83) | CHRM2ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL24083614 | 0.77 | MAOA (0.55) | CHRM2ALDH1A1SMN1; SMN2VNN1MEN1 | |
| SCHEMBL4928792 | 0.76 | CYP4A11 (0.66) | CHRM2ALDH1A1LMNASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL948529 | 0.76 | CHRM2 (0.62) | CHRM2ALDH1A1LMNAMCHR1SMN1; SMN2 | |
| SCHEMBL9269956 | 0.76 | MCHR1 (0.47) | CHRM2ALDH1A1LMNAMCHR1SMN1; SMN2 | |
| SCHEMBL11300822 | 0.76 | CHRM2 (0.62) | CHRM2ALDH1A1LMNAMCHR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-5753664-A | ANTITUMOR AGENTS, PYRIMIDONES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |