Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ASPH | Q12797 | 2/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011778 | 0.81 | KEAP1 (0.35) | KDM4EASPHKDM8KEAP1NFE2L2 | |
| SCHEMBL7010260 | 0.80 | HSD17B10 (0.49) | HSD17B10KDM4EKEAP1NFE2L2MAPT | |
| SCHEMBL7012967 | 0.77 | KEAP1 (0.34) | HSD17B10TSHRKDM4EASPHKDM8 | |
| SCHEMBL7010444 | 0.77 | ALDH1A1 (0.39) | KDM4EMAPT | |
| SCHEMBL10515953 | 0.75 | KEAP1 (0.42) | TSHRKDM4EASPHKDM8KEAP1 | |
| SCHEMBL7006318 | 0.71 | KEAP1 (0.37) | HSD17B10TSHRKDM4EASPHKDM8 | |
| SCHEMBL8056962 | 0.71 | KEAP1 (0.42) | TSHRKDM4EASPHKDM8KEAP1 | |
| SCHEMBL31034649 | 0.71 | KEAP1 (0.42) | TSHRKDM4EASPHKDM8KEAP1 | |
| SCHEMBL23496686 | 0.70 | KEAP1 (0.47) | HSD17B10TSHRKDM4EASPHKDM8 | |
| SCHEMBL2670263 | 0.70 | KEAP1 (0.39) | HSD17B10TSHRKDM4EASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |