Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816116 | 0.91 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL2818982 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL29492994 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL126043 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL5085753 | 0.78 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDMAPTGAA | |
| SCHEMBL9864743 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL4248903 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL821898 | 0.76 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL380146 | 0.76 | TSHR (0.57) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL403210 | 0.76 | CA12 (0.71) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815859-B1 | INTIMAL THICKENING INHIBITORS | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-5977130-A | CARDIOVASCULAR DISORDERS | TAIHO PHARMEUTICAL CO., LTD. (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0815859-A1 | INTIMAL THICKENING INHIBITORS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1998-01-07 | — | — | EP | disclosed |