Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CFTR | P13569 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70467 | 0.86 | TSHR (0.59) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL8834011 | 0.83 | CA1 (0.50) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL29946551 | 0.82 | TSHR (0.55) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL16618748 | 0.82 | TSHR (0.55) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL498003 | 0.82 | TSHR (0.55) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL181067 | 0.82 | ALDH1A1 (0.55) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL4652940 | 0.82 | NPC1 (0.37) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| Dimethyl Phthalate SCHEMBL34630 | 0.80 | TSHR (0.74) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| Dimethyl Phthalate SCHEMBL790124 | 0.80 | TSHR (0.74) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| Dimethyl Phthalate SCHEMBL29669976 | 0.80 | TSHR (0.74) | TSHRLMNAALDH1A1HSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 723 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329913-B2 | Carbazole derivative, solvate thereof, or pharmaceutically acceptable salt thereof | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2012-12-11 | — | — | US | claimed |
| EP-1852433-B1 | CARBAZOLE DERIVATIVE, SOLVATE THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ZERIA PHARM CO LTD (JP) | 2011-11-23 | — | — | EP | claimed |
| US-20100286210-A1 | Carbazole derivative, solvate thereof, or pharmaceutically acceptable salt thereof | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2010-11-11 | — | — | US | claimed |
| US-7560459-B2 | Substituted sulfamate anticonvulsant derivatives | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-07-14 | — | — | US | claimed |
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| EP-1852433-A1 | CARBAZOLE DERIVATIVE, SOLVATE THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Zeria Pharmaceutical Co., Ltd. (JP) | 2007-11-07 | — | — | EP | claimed |
| US-7060725-B2 | Substituted sulfamate anticonvulsant derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-06-13 | — | — | US | claimed |
| US-20060058373-A1 | Novel substituted sulfamate anticonvulsant derivatives | ABDEL-MAGID AHMED | 2006-03-16 | — | — | US | claimed |
| EP-1506212-A2 | NOVEL SUBSTITUTED SULFAMATE ANTICONVULSANT DERIVATIVES | Ortho-McNeil Pharmaceutical, Inc. (US) | 2005-02-16 | — | — | EP | claimed |
| US-20040038911-A1 | Novel substituted sulfamate anticonvulsant derivatives | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-02-26 | — | — | US | claimed |
| EP-0394829-A1 | Renin-inhibiting dipeptides, process to synthetize them, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-31 | — | — | EP | claimed |
| US-4855286-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | claimed |
| US-4754034-A | RECORDING MATERIALS, PRESSURE SENSITIVE, THERMOREACTIVE, ELECTROCHROMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1988-06-28 | — | — | US | claimed |
| EP-0180813-B1 | CHROMOGENIC 4,4-DIARYLDIHYDROCHINAZOLONES, THEIR PREPARATION AND USE | BAYER AG (DE) | 1988-06-01 | — | — | EP | claimed |
| EP-0255082-A2 | Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-03 | — | — | EP | claimed |
| EP-0239874-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-10-07 | — | — | EP | claimed |
| EP-0230242-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-29 | — | — | EP | claimed |
| EP-0180813-A1 | Chromogenic 4,4-diaryldihydrochinazolones, their preparation and use | BAYER AG (DE) | 1986-05-14 | — | — | EP | claimed |
| US-4548926-A | RENIN INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1985-10-22 | — | — | US | claimed |
| EP-0128762-A2 | New hypotensive peptides, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1984-12-19 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038911-A1 | Novel substituted sulfamate anticonvulsant derivatives | SULT1E1, SULT2A1, GRIK5 | TSHR 2222/4885LMNA 4640/4885ALDH1A1 511/4885 |
| US-20100286210-A1 | Carbazole derivative, solvate thereof, or pharmaceutically acceptable salt thereof | CEL, LIPC, CES1 | TSHR 2848/4885LMNA 1355/4885ALDH1A1 551/4885 |
| US-20060058373-A1 | Novel substituted sulfamate anticonvulsant derivatives | SULT1E1, CACNA1A, SULT2A1 | TSHR 1085/4885LMNA 4383/4885ALDH1A1 1011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.