Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ1A | Q9NRL2 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | DDX3X | O00571 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020816 | 0.81 | HSP90AA1 (0.63) | KMT2AMEN1MAPTHTTRAB9A | |
| SCHEMBL7017485 | 0.77 | EGLN1 (0.52) | MAPTRAB9AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL7011986 | 0.77 | HSP90AA1 (0.51) | KMT2AMEN1POLBRAB9AL3MBTL1 | |
| SCHEMBL16672104 | 0.73 | MEN1 (0.63) | KMT2AMEN1MAPTPOLBCTDSP1 | |
| SCHEMBL12694410 | 0.73 | MEN1 (0.63) | KMT2AMEN1MAPTPOLBCTDSP1 | |
| SCHEMBL30858696 | 0.73 | MEN1 (0.63) | KMT2AMEN1MAPTPOLBCTDSP1 | |
| SCHEMBL14112022 | 0.72 | L3MBTL1 (0.69) | BAZ1AKMT2AMEN1MAPTPOLB | |
| SCHEMBL5892586 | 0.72 | SMN1; SMN2 (0.71) | KMT2AMEN1MAPTPOLBCTDSP1 | |
| SCHEMBL10437702 | 0.72 | MEN1 (0.65) | KMT2AMEN1MAPTPOLBCTDSP1 | |
| SCHEMBL7015297 | 0.72 | NPC1 (0.49) | KMT2AMEN1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155017-B1 | [1,8] NAPHTHYRIDINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | SHIRE BIOCHEM INC (CA) | 2003-01-15 | — | — | EP | claimed |