Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020816 | 0.90 | HSP90AA1 (0.63) | HSP90AA1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL7017485 | 0.86 | EGLN1 (0.52) | HSP90AA1LMNAKDM4ENPC1RAB9A | |
| SCHEMBL7015297 | 0.81 | NPC1 (0.49) | HSP90AA1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL28769096 | 0.78 | HSD17B10 (0.49) | LMNAKDM4EKMT2AMEN1POLB | |
| SCHEMBL7015247 | 0.77 | NPC1 (0.51) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL7017772 | 0.77 | NPC1 (0.50) | HSP90AA1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL7012199 | 0.77 | KDM4E (0.58) | LMNAKDM4EKMT2AMEN1POLB | |
| SCHEMBL7014400 | 0.77 | BAZ1A (0.59) | HSP90AA1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL27575240 | 0.74 | KDM4E (0.53) | HSP90AA1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL7018630 | 0.74 | NPC1 (0.53) | KDM4EKMT2AMEN1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155017-B1 | [1,8] NAPHTHYRIDINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | SHIRE BIOCHEM INC (CA) | 2003-01-15 | — | — | EP | claimed |