Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020816 | 0.88 | HSP90AA1 (0.63) | EGLN1HSP90AA1NPC1RAB9APKM | |
| SCHEMBL7011986 | 0.86 | HSP90AA1 (0.51) | EGLN1HSP90AA1NPC1RAB9APRKCI | |
| SCHEMBL5775246 | 0.80 | ABL1 (0.62) | PRKCI | |
| SCHEMBL7021606 | 0.79 | EPHX1 (0.52) | PKMNAMPTLMNAMAPT | |
| SCHEMBL7011976 | 0.78 | RAB9A (0.58) | EGLN1NPC1RAB9APKMNAMPT | |
| SCHEMBL7015297 | 0.78 | NPC1 (0.49) | HSP90AA1TSHRNPC1RAB9APKM | |
| SCHEMBL7014400 | 0.77 | BAZ1A (0.59) | HSP90AA1NPC1RAB9ALMNAKCNH2 | |
| SCHEMBL7015247 | 0.75 | NPC1 (0.51) | NPC1RAB9ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7017772 | 0.75 | NPC1 (0.50) | HSP90AA1TSHRNPC1RAB9ALMNA | |
| SCHEMBL241619 | 0.73 | NPC1 (0.63) | NPC1RAB9APKMNAMPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155017-B1 | [1,8] NAPHTHYRIDINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | SHIRE BIOCHEM INC (CA) | 2003-01-15 | — | — | EP | claimed |