Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2078975 | 0.81 | DHODH (0.58) | KDM4EMAPTMEN1KMT2ATDP1 | |
| SCHEMBL6517016 | 0.81 | HPGD (0.53) | KDM4EMAPTMEN1KMT2ASLC6A2 | |
| SCHEMBL7414885 | 0.80 | MTNR1A (0.46) | KDM4EMAPTL3MBTL1KMT2ANR4A2 | |
| SCHEMBL19857562 | 0.80 | PDPK1 (0.53) | KDM4EALDH1A1HSD17B10DHODH | |
| SCHEMBL29696398 | 0.80 | PDPK1 (0.53) | KDM4EALDH1A1HSD17B10DHODH | |
| SCHEMBL25932265 | 0.80 | DHODH (0.57) | MAPTKMT2ATDP1SLC6A2SLC6A4 | |
| SCHEMBL7877965 | 0.80 | KDM4E (0.56) | KDM4EMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL5414816 | 0.79 | ALDH1A1 (0.44) | KDM4EMAPTRXFP1NR4A2SLC6A2 | |
| SCHEMBL7422427 | 0.79 | ALDH1A1 (0.52) | KDM4EMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL7416024 | 0.78 | MTNR1A (0.50) | KDM4EMAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1327631-A2 | Fused heterocyclic compounds, their production and use as angiotensin II antagonists | Takeda Chemical Industries, Ltd. (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-0518033-B1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-5389641-A | Fused heterocyclic compounds, having angiotensin II antagonistic activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |