Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701463 | 0.83 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2HTTPOLBPDE2A | |
| SCHEMBL1694756 | 0.81 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTKMT2APDE2A | |
| SCHEMBL13227333 | 0.80 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HTTPOLBPDE2A | |
| SCHEMBL7213963 | 0.80 | CA2 (0.47) | ALDH1A1SMN1; SMN2HTTPOLBKMT2A | |
| SCHEMBL29452062 | 0.80 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HTTPOLBKMT2A | |
| SCHEMBL7212515 | 0.80 | CYP3A4 (0.48) | ALDH1A1SMN1; SMN2HTTPOLBKMT2A | |
| SCHEMBL8351509 | 0.80 | MCOLN3 (0.64) | ALDH1A1SMN1; SMN2HTTKMT2AKDM4E | |
| SCHEMBL9306878 | 0.79 | HTT (0.53) | ALDH1A1SMN1; SMN2HTTPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL5804305 | 0.78 | MCOLN3 (0.62) | ALDH1A1SMN1; SMN2HTTKMT2AKDM4E | |
| SCHEMBL1538438 | 0.78 | KMT2A (0.56) | ALDH1A1SMN1; SMN2KMT2AKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131335-A1 | SURFACE ACTIVE ADJUVANT | RHODIA OPERATIONS (FR) | 2020-04-30 | — | — | US | disclosed |
| EP-3612604-A1 | SURFACE ACTIVE ADJUVANT | Rhodia Operations (FR) | 2020-02-26 | — | — | EP | disclosed |
| WO-2020035124-A1 | SURFACE ACTIVE ADJUVANT FOR COATINGS | RHODIA OPERATIONS (FR) | 2020-02-20 | — | — | WO | disclosed |
| WO-2018193009-A1 | SURFACE ACTIVE ADJUVANT | RHODIA OPERATIONS (FR) | 2018-10-25 | — | — | WO | disclosed |
| EP-2229395-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
| EP-2139851-A2 | SUBSTITUTED AMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2010-01-06 | — | — | EP | disclosed |
| WO-2009090054-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2009-07-23 | — | — | WO | disclosed |
| US-20090030038-A1 | Novel 8-Sulfonylamino-3 Aminosubstituted Chroman or Tetrahydronaphtalene Derivatives Modulating the 5Ht6 Receptor | ASTRAZENECA AB (SE) | 2009-01-29 | — | — | US | disclosed |
| WO-2008131946-A2 | SUBSTITUTED AMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2008-11-06 | — | — | WO | disclosed |
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| US-6423717-B1 | NERVOUS SYSTEM DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-07-23 | — | — | US | disclosed |
| US-5328884-A | Salicylic acid salt,and amide or sulfonamide as developer | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| US-5250108-A | Mixture of salicylic acid salt, amide and sulfonamide compounds | KANZAKI PAPER MANUFACTURING CO. LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030038-A1 | Novel 8-Sulfonylamino-3 Aminosubstituted Chroman or Tetrahydronaphtalene Derivatives Modulating the 5Ht6 Receptor | HTR6, HTR1A, HTR1D | ALDH1A1 2701/4885SMN1; SMN2 1687/4885HTT 417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.