Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166734 | 0.85 | ALDH1A1 (0.41) | NPSR1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL110074 | 0.84 | NPSR1 (0.44) | NPSR1SMN1; SMN2MAPTHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL15206614 | 0.83 | SMN1; SMN2 (0.42) | NPSR1SMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL17603797 | 0.80 | SMN1; SMN2 (0.41) | NPSR1SMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL118992 | 0.78 | NPSR1 (0.48) | NPSR1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL29556424 | 0.78 | NPSR1 (0.48) | NPSR1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL257010 | 0.77 | ALDH1A1 (0.38) | SMN1; SMN2MAPTHTTALDH1A1PKM | |
| SCHEMBL13256088 | 0.77 | NPSR1 (0.47) | NPSR1SMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL19627710 | 0.77 | NPSR1 (0.47) | NPSR1SMN1; SMN2ALDH1A1KDM4EPKM | |
| SCHEMBL7012885 | 0.77 | NPSR1 (0.41) | NPSR1SMN1; SMN2MAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1327631-A2 | Fused heterocyclic compounds, their production and use as angiotensin II antagonists | Takeda Chemical Industries, Ltd. (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-0518033-B1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-5389641-A | Fused heterocyclic compounds, having angiotensin II antagonistic activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0518033-A1 | Fused heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |