SCHEMBL701486

SCHEMBL701486

O=C(C=Cc1ccc(Cl)cc1)O[C@H]1CCCC[C@@H]1OC(=O)/C=C/c1ccc(Cl)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.52
CYP1A2 P05177 1/20 0.51
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
MAOB P27338 4/20 0.46
MAOA P21397 1/20 0.46
HDAC2 Q92769 1/20 0.44
LMNA P02545 2/20 0.43
HTT P42858 1/20 0.43
HRH3 Q9Y5N1 1/20 0.43
MAPK1 P28482 2/20 0.43
CXCL12 P48061 1/20 0.43
SLC37A4 O43826 1/20 0.43
POLB P06746 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
PKM P14618 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17785158 0.86 USP2 (0.51) USP2CYP1A2KMT2AMAOBMAOA
SCHEMBL17785157 0.86 USP2 (0.51) USP2CYP1A2KMT2AMAOBMAOA
SCHEMBL699090 0.84 CYP2C19 (0.51) CYP1A2MEN1KMT2AHDAC2LMNA
SCHEMBL18364671 0.83 HTT (0.61) MEN1KMT2AHDAC2LMNAHTT
SCHEMBL8019037 0.79 APP (0.62) HDAC2TSHR
SCHEMBL20306019 0.79 MAOA (0.58) MEN1KMT2AMAOBMAOAHDAC2
SCHEMBL11850021 0.74 USP2 (0.61) USP2CYP1A2MEN1KMT2ALMNA
SCHEMBL11850030 0.74 USP2 (0.61) USP2CYP1A2MEN1KMT2ALMNA
SCHEMBL20801608 0.73 HTT (0.43) USP2CYP1A2MAOBMAOALMNA
SCHEMBL20801607 0.73 HTT (0.43) USP2CYP1A2MAOBMAOALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2466582-B1 Optical Data Storage Media And Methods For Using The Same GEN ELECTRIC (US) 2014-02-26 EP disclosed
EP-2423917-B1 Use of chemically bonded dyes in holographic data storage media GEN ELECTRIC (US) 2013-08-07 EP disclosed
EP-2290651-B1 Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC (US) 2012-10-10 EP disclosed
EP-2290408-B1 Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC (US) 2012-08-15 EP disclosed
EP-2466582-A1 Optical Data Storage Media And Methods For Using The Same General Electric Company (US) 2012-06-20 EP disclosed
US-20120147724-A1 OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE SAME GENERAL ELECTRIC COMPANY (US) 2012-06-14 US disclosed
EP-2423917-A2 Use of chemically bonded dyes in holographic data storage media General Electric Company (US) 2012-02-29 EP disclosed
US-20110053055-A1 COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2011-03-03 US disclosed
EP-2290650-A1 Optical data storage media and methods for using the same General Electric Company (US) 2011-03-02 EP disclosed
EP-2290408-A1 Compositions, optical data storage media and methods for using the optical data storage media General Electric Company (US) 2011-03-02 EP disclosed
EP-2290651-A1 Compositions, optical data storage media and methods for using the optical data storage media General Electric Company (US) 2011-03-02 EP disclosed