Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18364671 | 0.94 | HTT (0.61) | HTTTRPM8RAB9ATHRBMAPT | |
| SCHEMBL600597 | 0.82 | HTT (0.70) | HTTTRPM8RAB9ATHRBMAPT | |
| SCHEMBL154420 | 0.82 | HTT (0.70) | HTTTRPM8RAB9ATHRBMAPT | |
| SCHEMBL13899764 | 0.82 | F3 (0.57) | HTTTRPM8RAB9ATHRBMAPT | |
| SCHEMBL17785153 | 0.80 | TRPM8 (0.57) | MAOAMAOBHTTTRPM8RAB9A | |
| SCHEMBL17785154 | 0.80 | TRPM8 (0.57) | MAOAMAOBHTTTRPM8RAB9A | |
| SCHEMBL12608600 | 0.80 | HTT (0.67) | HTTTRPM8RAB9ATHRBMAPT | |
| SCHEMBL701486 | 0.79 | USP2 (0.52) | MAOAMAOBHTTTP53MEN1 | |
| SCHEMBL699090 | 0.78 | CYP2C19 (0.51) | TRPM8RAB9AMAPTSMN1; SMN2RELA | |
| SCHEMBL11999799 | 0.78 | F3 (0.86) | MAOAMAOBRAB9ATHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10007042-B2 | Composition, light reflecting film, luminance-improving film, backlight unit, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2018-06-26 | — | — | US | disclosed |