Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5536563 | 0.94 | CTSS (0.72) | CTSSCD74 | |
| SCHEMBL4719347 | 0.91 | CTSS (0.70) | CTSSCD74 | |
| SCHEMBL5530629 | 0.91 | CTSS (0.69) | CTSSCD74 | |
| SCHEMBL5531884 | 0.91 | CTSS (0.66) | CTSSCD74 | |
| SCHEMBL5533874 | 0.90 | CTSS (0.67) | CTSSCD74 | |
| SCHEMBL5534114 | 0.89 | CTSS (0.66) | CTSSCD74 | |
| SCHEMBL5534463 | 0.89 | CTSS (0.66) | CTSSCD74 | |
| SCHEMBL5537073 | 0.88 | CTSS (0.67) | CTSSCD74 | |
| SCHEMBL4717007 | 0.88 | CTSS (0.73) | CTSSCD74 | |
| SCHEMBL5787973 | 0.87 | CTSS (0.64) | CTSSCD74 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309593-A2 | SUBSTITUTED PYRAZOLES | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-05-14 | — | — | EP | disclosed |
| US-20030078419-A1 | Substituted pyrazoles | ORTHO MCNEIL PHARMACEUTICAL, INC. | 2003-04-24 | — | — | US | disclosed |
| WO-2002014315-A2 | SUBSTITUTED PYRAZOLES | ORTHO MCNEIL PHARMACEUTICAL, INC. (US) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078419-A1 | Substituted pyrazoles | CTSS, CTSZ, CTSV | CTSS 1/4885CD74 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.