Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007960 | 0.92 | LCK (0.40) | DNM1FDPSCA1LCKPPARD | |
| SCHEMBL2453892 | 0.83 | FDPS (0.35) | FDPSTSHRTDP1 | |
| SCHEMBL2599831 | 0.76 | — | — | |
| SCHEMBL6384338 | 0.74 | GABRR1 (0.32) | FDPS | |
| SCHEMBL6447998 | 0.72 | DNM1 (0.46) | DNM1FDPSTSHRSMN1; SMN2CA2 | |
| SCHEMBL316766 | 0.71 | — | — | |
| SCHEMBL5949130 | 0.70 | DNM1 (0.38) | DNM1FDPSTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL5948622 | 0.68 | ALDH1A1 (0.37) | DNM1FDPSTSHRSMN1; SMN2CA2 | |
| SCHEMBL8099290 | 0.68 | DNM1 (0.36) | DNM1FDPSTSHRSMN1; SMN2CA2 | |
| SCHEMBL28703222 | 0.68 | DNM1 (0.36) | DNM1FDPSTSHRSMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013109388-A2 | 1,5-NAPHTHYRIDINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2013-07-25 | — | — | WO | disclosed |
| EP-0815859-B1 | INTIMAL THICKENING INHIBITORS | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-5977130-A | CARDIOVASCULAR DISORDERS | TAIHO PHARMEUTICAL CO., LTD. (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0815859-A1 | INTIMAL THICKENING INHIBITORS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1998-01-07 | — | — | EP | disclosed |