Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6485358 | 0.88 | MTNR1A (0.51) | LMNAMTNR1AMEN1KMT2APPARG | |
| SCHEMBL6477969 | 0.86 | MTNR1A (0.48) | FFAR1MTNR1APPARGPPARDPPARA | |
| SCHEMBL6477814 | 0.81 | PPARG (0.58) | LMNAMTNR1AMEN1KMT2APPARG | |
| SCHEMBL6476520 | 0.81 | PPARG (0.56) | FFAR1MTNR1APPARGPPARDPPARA | |
| SCHEMBL2127227 | 0.80 | MTNR1A (0.62) | LMNAMTNR1AITGB3ITGAVITGB5 | |
| SCHEMBL6475861 | 0.79 | MTNR1A (0.47) | FFAR1MTNR1APPARGTBXAS1 | |
| SCHEMBL7016021 | 0.79 | TBXAS1 (0.57) | LMNAMTNR1AMEN1KMT2ATBXAS1 | |
| SCHEMBL7016025 | 0.79 | TBXAS1 (0.57) | LMNAMTNR1AMEN1KMT2ATBXAS1 | |
| SCHEMBL28922916 | 0.78 | MTNR1A (0.59) | LMNAMTNR1AFFAR4MEN1KMT2A | |
| SCHEMBL6486014 | 0.77 | MTNR1A (0.47) | LMNAL3MBTL1MTNR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252150-B1 | HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2003-06-04 | — | — | EP | disclosed |