Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21208597 | 0.88 | OPRM1 (0.51) | MEN1KMT2AMAPK1HSP90AA1HSP90B1 | |
| Hydrochloric Acid SCHEMBL7016527 | 0.87 | OPRM1 (0.50) | MEN1KMT2AMAPK1HSP90AA1HSP90B1 | |
| SCHEMBL7020485 | 0.84 | RAB9A (0.53) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL30406199 | 0.84 | OPRM1 (0.47) | MEN1KMT2AMAPK1HSP90AA1HSP90B1 | |
| SCHEMBL12803808 | 0.79 | SMN1; SMN2 (0.50) | MEN1KMT2AMAPK1HSP90AA1HSP90B1 | |
| SCHEMBL12604389 | 0.78 | HSP90B1 (0.51) | MEN1KMT2AMAPK1HSP90AA1HSP90B1 | |
| SCHEMBL12604380 | 0.76 | HSP90AA1 (0.45) | MEN1KMT2AMAPK1HSP90AA1HSP90B1 | |
| SCHEMBL1051652 | 0.76 | ALDH1A1 (0.54) | KMT2AMAPK1HSP90AA1HSP90B1RAB9A | |
| SCHEMBL7868637 | 0.76 | HSP90AA1 (0.52) | MEN1KMT2AMAPK1HSP90AA1HSP90B1 | |
| SCHEMBL703931 | 0.75 | MAPT (0.72) | KMT2AMAPTRAB9ATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972769-B1 | NOVEL AMIDE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-6177454-B1 | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2001-01-23 | — | — | US | disclosed |
| US-6048884-A | ANTIDIABETIC AGENTS; HYPOGLYCEMIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0972769-A1 | NOVEL AMIDE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |