Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015959 | 0.90 | TP53 (0.44) | MAPTTP53POLBPIK3CDPIK3CB | |
| SCHEMBL7015451 | 0.83 | SRD5A2 (0.44) | MAPTTP53POLBPIK3CDPIK3CB | |
| SCHEMBL7015350 | 0.79 | TP53 (0.44) | MAPTTP53POLBPIK3CDPIK3CB | |
| Hydrochloric Acid SCHEMBL7013530 | 0.78 | L3MBTL1 (0.39) | MAPTTP53PIK3CDPIK3CBHDAC3 | |
| SCHEMBL7014282 | 0.78 | TP53 (0.41) | MAPTTP53POLBPIK3CDPIK3CB | |
| SCHEMBL7016868 | 0.77 | ENPP2 (0.42) | MAPTTP53POLBPIK3CDPIK3CB | |
| SCHEMBL8642392 | 0.77 | MAPT (0.39) | MAPTTP53POLBCYP19A1TDP1 | |
| SCHEMBL7016044 | 0.75 | PIK3CD (0.55) | MAPTTP53POLBPIK3CDPIK3CB | |
| SCHEMBL7016621 | 0.72 | TP53 (0.42) | MAPTTP53POLBPIK3CDPIK3CB | |
| SCHEMBL7016280 | 0.71 | PIK3CD (0.43) | MAPTTP53POLBPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |