Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18071109 | 0.94 | USP2 (0.45) | TSHRUSP2CYP2C9WDR5LMNA | |
| SCHEMBL15255039 | 0.92 | CYP2C9 (0.52) | TSHRCYP2C9LMNAMAPTKDM4E | |
| SCHEMBL18969804 | 0.82 | LMNA (0.64) | CYP2C9LMNACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL31032827 | 0.82 | LMNA (0.64) | CYP2C9LMNACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL96351 | 0.82 | LMNA (0.64) | CYP2C9LMNACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11920836 | 0.82 | FFAR1 (0.51) | TSHRUSP2CYP2C9WDR5LMNA | |
| SCHEMBL1496690 | 0.80 | TSHR (0.62) | TSHRUSP2CYP2C9LMNAMEN1 | |
| SCHEMBL14934283 | 0.80 | TSHR (0.62) | TSHRUSP2CYP2C9LMNAMEN1 | |
| SCHEMBL5987262 | 0.80 | USP2 (0.45) | TSHRUSP2CYP2C9WDR5LMNA | |
| SCHEMBL16790621 | 0.80 | SCN4A (0.55) | TSHRUSP2CYP2C9WDR5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190185619-A1 | POLYESTER-BASED POLYMERS HAVING IMPROVED HYDROLYTIC STABILITY | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-06-20 | — | — | US | disclosed |
| US-9724322-B2 | 4-(phenoxyalkyl)thio)-phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA N.V. (BE) | 2017-08-08 | — | — | US | disclosed |
| US-20160199342-A1 | 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | CYMABAY THERAPEUTICS, INC. | 2016-07-14 | — | — | US | disclosed |
| US-8518997-B2 | 4-(phenoxyalkyl)thio)-phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA N.V. (BE) | 2013-08-27 | — | — | US | disclosed |
| US-8367756-B2 | Stabilized coating dispersions for porous inkjet recording media | EASTMAN KODAK COMPANY (US) | 2013-02-05 | — | — | US | disclosed |
| US-20120122988-A1 | 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | CYMABAY THERAPEUTICS, INC. | 2012-05-17 | — | — | US | disclosed |
| US-20090170980-A1 | STABILIZED COATING DISPERSIONS FOR POROUS INKJET RECORDING MEDIA | QUALEX INC. | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122988-A1 | 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | PPARA, PPARG, PPARD | TSHR 307/4885USP2 2009/4885CYP2C9 2708/4885 |
| US-20160199342-A1 | 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | PPARA, PPARG, PPARD | TSHR 307/4885USP2 2009/4885CYP2C9 2708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.