SCHEMBL18969804

SCHEMBL18969804

C[C@H](CO)COc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.64
MAOA P21397 1/20 0.53
PTGS1 P23219 1/20 0.53
MTNR1A P48039 3/20 0.51
MTNR1B P49286 3/20 0.51
CYP2D6 P10635 3/20 0.51
ADRB2 P07550 1/20 0.51
ADRB1 P08588 1/20 0.51
ADRB3 P13945 1/20 0.51
ALDH1A1 P00352 1/20 0.48
RECQL P46063 1/20 0.48
FFAR1 O14842 1/20 0.47
SCN4A P35499 2/20 0.47
TRPA1 O75762 2/20 0.47
NPC1 O15118 1/20 0.46
MTOR P42345 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31032827 1.00 LMNA (0.64) LMNAMAOAPTGS1MTNR1AMTNR1B
SCHEMBL96351 1.00 LMNA (0.64) LMNAMAOAPTGS1MTNR1AMTNR1B
SCHEMBL15255039 0.89 CYP2C9 (0.52) LMNAPTGS1CYP2D6FFAR1NPC1
SCHEMBL13385106 0.87 LMNA (0.68) LMNAMAOAPTGS1MTNR1AMTNR1B
SCHEMBL14595237 0.86 TSHR (0.59) LMNAMTNR1AMTNR1BADRB2ADRB1
SCHEMBL7015375 0.82 TSHR (0.49) LMNACYP2D6RECQLFFAR1NPC1
SCHEMBL15958920 0.81 ADRB2 (0.59) ADRB2ADRB1MAPK1
SCHEMBL28294103 0.81 FFAR1 (0.61) LMNAMAOAPTGS1MTNR1AMTNR1B
SCHEMBL2500159 0.81 FFAR1 (0.61) LMNAMAOAPTGS1MTNR1AMTNR1B
SCHEMBL24741070 0.80 ALDH1A1 (0.55) LMNAMTNR1AMTNR1BALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024178219-A1 1-ACYL-3-AMINOINDAZOLES FOR TREATING CYSTIC FIBROSIS SHOICHET BRIAN (US) 2024-08-29 WO disclosed
US-11518876-B2 Photosensitive resin composition and photosensitive dry film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-12-06 US disclosed
US-10669444-B2 Coating formulation with an open time additive DOW GLOBAL TECHNOLOGIES LLC (US) 2020-06-02 US disclosed
US-20200140678-A1 PHOTOSENSITIVE RESIN COMPOSITION AND PHOTOSENSITIVE DRY FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-05-07 US disclosed
US-20190055422-A1 COATING FORMULATION WITH AN OPEN TIME ADDITIVE DOW GLOBAL TECHNOLOGIES LLC 2019-02-21 US disclosed
US-9969817-B2 Phenyl glycidyl ether adduct of maltodextrin ROHM AND HAAS COMPANY (US) 2018-05-15 US disclosed
WO-2017155845-A1 COATING FORMULATION WITH AN OPEN TIME ADDITIVE DOW GLOBAL TECHNOLOGIES LLC (US) 2017-09-14 WO disclosed
EP-3181589-A1 PHENYL GLYCIDYL ETHER ADDUCT OF MALTODEXTRIN ROHM AND HAAS COMPANY (US) 2017-06-21 EP disclosed
US-20170166663-A1 PHENYL GLYCIDYL ETHER ADDUCT OF MALTODEXTRIN ROHM & HAAS (US) 2017-06-15 US disclosed
US-20170166663-A1 PHENYL GLYCIDYL ETHER ADDUCT OF MALTODEXTRIN ROHM & HAAS (US) 2017-06-15 US disclosed