Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.68 |
| ▸ | ITGAV | P06756 | 15/20 | 0.68 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.53 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.52 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.52 |
| ▸ | ITGB8 | P26012 | 4/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549076 | 0.88 | ITGB3 (0.74) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL13720083 | 0.87 | ITGAV (0.69) | ITGB3ITGAVCXCR4ITGB5ITGB6 | |
| SCHEMBL5500945 | 0.83 | ITGAV (0.67) | ITGB3ITGAVCXCR4ITGB5ITGB6 | |
| SCHEMBL6426136 | 0.83 | ITGAV (0.71) | ITGB3ITGAVCXCR4ITGB5ITGB6 | |
| SCHEMBL7587029 | 0.83 | ITGAV (0.61) | ITGB3ITGAVCXCR4ITGB5ITGB6 | |
| SCHEMBL22893669 | 0.83 | ITGAV (0.61) | ITGB3ITGAVCXCR4ITGB6 | |
| SCHEMBL7377654 | 0.82 | ITGAV (0.69) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL22029444 | 0.82 | ITGB3 (0.90) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL21706071 | 0.82 | ITGB3 (0.90) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL6421618 | 0.81 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGB6ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946165-B1 | INTEGRIN ANTAGONISTS | MERCK & CO INC (US) | 2003-04-09 | — | — | EP | disclosed |