Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20836220 | 0.88 | CES2 (0.56) | SRD5A2MEP1BL3MBTL1ATMTDP1 | |
| SCHEMBL185962 | 0.88 | ATM (0.52) | SRD5A2MEP1AMEP1BCNR2L3MBTL1 | |
| SCHEMBL29572523 | 0.88 | ATM (0.52) | SRD5A2MEP1AMEP1BCNR2L3MBTL1 | |
| SCHEMBL435297 | 0.86 | L3MBTL1 (0.63) | SRD5A2CNR2L3MBTL1ATMTDP1 | |
| SCHEMBL29728644 | 0.86 | L3MBTL1 (0.63) | SRD5A2CNR2L3MBTL1ATMTDP1 | |
| SCHEMBL11493619 | 0.83 | MEP1B (0.46) | SRD5A2MAPK1MEP1BL3MBTL1ATM | |
| SCHEMBL14302252 | 0.83 | SRD5A2 (0.47) | SRD5A2MAPK1MRGPRX4CNR2L3MBTL1 | |
| SCHEMBL2931832 | 0.83 | CES2 (0.51) | L3MBTL1ATMTDP1CES2CES1 | |
| SCHEMBL1744667 | 0.82 | SRD5A2 (0.57) | SRD5A2MAPK1GSK3BL3MBTL1MAPT | |
| SCHEMBL11541766 | 0.82 | L3MBTL1 (0.47) | SRD5A2MAPK1MRGPRX4CNR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-5753664-A | ANTITUMOR AGENTS, PYRIMIDONES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |
| EP-0151529-B1 | 5-(AMINO OR SUBSTITUTED AMINO)-1,2,3-TRIAZOLES | MERCK & CO. INC. (US) | 1991-09-18 | — | — | EP | disclosed |
| US-4590201-A | ANTICOCCIDIAL AGENT FOR ANIMALS PARTICULARLY FOR POULTRY | MERCK & CO., INC. (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0151529-A2 | 5-(Amino or substituted amino)-1,2,3-triazoles | MERCK & CO. INC. (US) | 1985-08-14 | — | — | EP | disclosed |
| US-4192890-A | Novel benzoylphenylacetic acid esters | ROUSSEL UCLAF (FR) | 1980-03-11 | — | — | US | disclosed |
| US-3995056-A | Butyric acid derivatives for treating pain and inflammation | ROUSSEL-UCLAF (FR) | 1976-11-30 | — | — | US | disclosed |
| US-3931302-A | ANTIINFLAMMATORY, ANALGESIC | ROUSSEL-UCLAF (FR) | 1976-01-06 | — | — | US | disclosed |