Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5273038 | 0.87 | MAPT (0.45) | MAPTL3MBTL1SMN1; SMN2ALDH1A1MGLL | |
| SCHEMBL6180649 | 0.86 | RAB9A (0.46) | MAPTL3MBTL1LMNAKMT2AMCHR1 | |
| SCHEMBL7010527 | 0.82 | STS (0.49) | MAPTL3MBTL1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7015669 | 0.76 | F10 (0.64) | F10 | |
| SCHEMBL4771588 | 0.76 | KMT2A (0.41) | MAPTEPHX2ALDH1A1MGLLHPGD | |
| SCHEMBL3125608 | 0.76 | CARM1 (0.49) | L3MBTL1SMN1; SMN2ALDH1A1MGLLKMT2A | |
| SCHEMBL1866719 | 0.75 | KMT2A (0.41) | L3MBTL1SMN1; SMN2ALDH1A1MGLLKMT2A | |
| SCHEMBL4097076 | 0.75 | CCR5 (0.42) | L3MBTL1ALDH1A1NOTUMMGLLHSD11B1 | |
| SCHEMBL16013886 | 0.75 | KMT2A (0.41) | MAPTL3MBTL1EPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL4777118 | 0.74 | GAA (0.49) | EPHX2SMN1; SMN2ALDH1A1MGLLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1302462-A1 | SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | SULT1E1, RRS1, SHH | MAPT 4719/4885F10 717/4885AHR 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.