Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | MGAM | O43451 | 7/20 | 0.64 |
| ▸ | GAA | P10253 | 7/20 | 0.64 |
| ▸ | SI | P14410 | 7/20 | 0.64 |
| ▸ | MGAM2 | Q2M2H8 | 7/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13253129 | 0.89 | MEN1 (0.74) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL7006159 | 0.85 | NR3C1 (0.69) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL6823826 | 0.84 | MEN1 (0.70) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL27984210 | 0.82 | MGAM (0.79) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL27984212 | 0.82 | MGAM (0.64) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL7011743 | 0.82 | MEN1 (0.64) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL31026318 | 0.80 | MEN1 (0.77) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL7012422 | 0.80 | MEN1 (0.77) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL3493768 | 0.80 | NR3C1 (0.61) | MEN1KMT2AMAPTTDP1MGAM | |
| SCHEMBL18662724 | 0.79 | MGAM (1.00) | MEN1KMT2AALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923581-B1 | 4-SUBSTITUTED BETA-CARBOLINES AS IMMUNOMODULATORS | BOEHRINGER INGELHEIM PHARMA (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6093723-A | AN IMMUNOMODULATOR FOR TREATING AND PREVENTING IMMUNE DISORDERS, INCLUDING AUTOIMMUNE DISEASE, INFLAMMATORY DISEASE, ORGAN TRANSPLANT REJECTION AND OTHER DISORDERS ASSOCIATED WITH IL-2 MEDIATED IMMUNE RESPONSE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-07-25 | — | — | US | disclosed |