Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | HTR2A | P28223 | 2/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | HTR2B | P41595 | 1/20 | 0.63 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | MGAM | O43451 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | SI | P14410 | 5/20 | 0.60 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823826 | 0.91 | MEN1 (0.70) | MEN1KMT2AMAPTUSP2ALDH1A1 | |
| SCHEMBL7015690 | 0.89 | MEN1 (0.73) | MEN1KMT2AMAPTUSP2ALDH1A1 | |
| SCHEMBL2073813 | 0.87 | CYP2D6 (0.67) | MEN1KMT2AMAPTUSP2ALDH1A1 | |
| SCHEMBL7011743 | 0.85 | MEN1 (0.64) | MEN1KMT2AMAPTUSP2ALDH1A1 | |
| SCHEMBL7006159 | 0.85 | NR3C1 (0.69) | MEN1KMT2AMAPTUSP2ALDH1A1 | |
| SCHEMBL2074209 | 0.85 | HTR2A (0.61) | MEN1KMT2AMAPTUSP2ALDH1A1 | |
| SCHEMBL14168804 | 0.84 | GPR84 (0.64) | MEN1KMT2AMAPTUSP2ALDH1A1 | |
| SCHEMBL1348944 | 0.83 | MGAM (0.64) | MEN1KMT2AMAPTUSP2ALDH1A1 | |
| SCHEMBL7967556 | 0.83 | GPR84 (0.62) | MEN1KMT2AMAPTUSP2ALDH1A1 | |
| SCHEMBL27682946 | 0.83 | GPR84 (0.62) | MEN1KMT2AMAPTUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100189648-A1 | INHIBITORS FOR DISRUPTING THE INTERACTION OF UBIQUITINATION RELATED ENZYMES AND USES THEREOF | HUANG LAN | 2010-07-29 | — | — | US | disclosed |
| US-20100189648-A1 | INHIBITORS FOR DISRUPTING THE INTERACTION OF UBIQUITINATION RELATED ENZYMES AND USES THEREOF | HUANG LAN | 2010-07-29 | — | — | US | disclosed |
| WO-2008052441-A1 | INHIBITORS FOR DISRUPTING THE INTERACTION OF UBIQUITINATION RELATED ENZYMES AND USES THEREOF | HUANG LAN (US) | 2008-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189648-A1 | INHIBITORS FOR DISRUPTING THE INTERACTION OF UBIQUITINATION RELATED ENZYMES AND USES THEREOF | MDM2, UBE2N, UBE2E1 | MEN1 3921/4885KMT2A 795/4885MAPT 2990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.