Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.69 |
| ▸ | PGR | P06401 | 1/20 | 0.69 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.69 |
| ▸ | AR | P10275 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | MGAM | O43451 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | SI | P14410 | 4/20 | 0.67 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.67 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13253129 | 0.85 | MEN1 (0.74) | NR3C1PGRNR3C2ARMEN1 | |
| SCHEMBL7015690 | 0.85 | MEN1 (0.73) | NR3C1PGRNR3C2ARMEN1 | |
| SCHEMBL31232970 | 0.84 | MGAM (0.67) | NR3C1PGRNR3C2ARMEN1 | |
| SCHEMBL2072650 | 0.82 | SLC6A4 (0.79) | NR3C1PGRNR3C2ARMEN1 | |
| SCHEMBL10836161 | 0.82 | NR3C1 (0.70) | NR3C1PGRNR3C2ARMEN1 | |
| SCHEMBL29802857 | 0.81 | NR3C1 (0.89) | NR3C1PGRNR3C2ARMEN1 | |
| SCHEMBL2546810 | 0.81 | NR3C1 (0.89) | NR3C1PGRNR3C2ARMEN1 | |
| SCHEMBL7011766 | 0.81 | KMT2A (0.72) | NR3C1PGRNR3C2ARMEN1 | |
| SCHEMBL6823826 | 0.81 | MEN1 (0.70) | MEN1KMT2AMAPTTDP1USP2 | |
| SCHEMBL4507869 | 0.81 | NR3C1 (0.64) | NR3C1PGRNR3C2ARMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11636918-B2 | Transcriptome-wide design of selective, bioactive small molecules targeting RNA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-04-25 | — | — | US | disclosed |
| US-20190156912-A1 | TRANSCRIPTOME-WIDE DESIGN OF SELECTIVE, BIOACTIVE SMALL MOLECULES TARGETING RNA | THE SCRIPPS RESEARCH INSTITUTE | 2019-05-23 | — | — | US | disclosed |
| US-20160188791-A1 | TRANSCRIPTOME-WIDE DESIGN OF SELECTIVE, BIOACTIVE SMALL MOLECULES TARGETING RNA | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-06-30 | — | — | US | disclosed |
| EP-0923581-B1 | 4-SUBSTITUTED BETA-CARBOLINES AS IMMUNOMODULATORS | BOEHRINGER INGELHEIM PHARMA (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6093723-A | AN IMMUNOMODULATOR FOR TREATING AND PREVENTING IMMUNE DISORDERS, INCLUDING AUTOIMMUNE DISEASE, INFLAMMATORY DISEASE, ORGAN TRANSPLANT REJECTION AND OTHER DISORDERS ASSOCIATED WITH IL-2 MEDIATED IMMUNE RESPONSE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160188791-A1 | TRANSCRIPTOME-WIDE DESIGN OF SELECTIVE, BIOACTIVE SMALL MOLECULES TARGETING RNA | MRPS27, RNGTT, MRPS22 | NR3C1 2981/4885PGR 3569/4885NR3C2 2498/4885 |
| US-11636918-B2 | Transcriptome-wide design of selective, bioactive small molecules targeting RNA | MRPS27, RNGTT, MRPS22 | NR3C1 2981/4885PGR 3569/4885NR3C2 2498/4885 |
| US-20190156912-A1 | TRANSCRIPTOME-WIDE DESIGN OF SELECTIVE, BIOACTIVE SMALL MOLECULES TARGETING RNA | MRPS27, RNGTT, MRPS22 | NR3C1 2981/4885PGR 3569/4885NR3C2 2498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.