Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264420 | 0.89 | POLB (0.34) | ALDH1A1MAPK1POLBTDP1MAPT | |
| SCHEMBL3246112 | 0.89 | ALDH1A1 (0.48) | ALDH1A1MAPK1TDP1MAPTL3MBTL1 | |
| SCHEMBL30542930 | 0.89 | ALDH1A1 (0.48) | ALDH1A1MAPK1TDP1MAPTL3MBTL1 | |
| SCHEMBL13978976 | 0.86 | POLB (0.33) | ALDH1A1MAPK1POLBTDP1MAPT | |
| SCHEMBL7240160 | 0.85 | POLB (0.39) | ALDH1A1MAPK1POLBTDP1MAPT | |
| SCHEMBL446563 | 0.85 | POLB (0.39) | ALDH1A1MAPK1POLBTDP1MAPT | |
| SCHEMBL28517525 | 0.85 | DNMT1 (0.40) | ALDH1A1MAPK1POLBTDP1MAPT | |
| SCHEMBL12781870 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPK1CYP1A2CYP2A6TSHR | |
| SCHEMBL1680196 | 0.84 | DHFR (0.43) | ALDH1A1POLBTDP1KDM4EPTPN1 | |
| SCHEMBL29351773 | 0.84 | DHFR (0.43) | ALDH1A1POLBTDP1KDM4EPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9871213-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2018-01-16 | — | — | US | disclosed |
| US-9871213-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2018-01-16 | — | — | US | disclosed |
| US-9871213-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2018-01-16 | — | — | US | disclosed |
| EP-1888706-B1 | ORGANIC ELECTROLUMINESCENT DEVICE AND BORIC ACID AND BORINIC ACID DERIVATIVES USED THEREIN | MERCK PATENT GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| EP-1888706-B1 | ORGANIC ELECTROLUMINESCENT DEVICE AND BORIC ACID AND BORINIC ACID DERIVATIVES USED THEREIN | MERCK PATENT GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| US-20160322570-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20160322570-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20160322570-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2016-11-03 | — | — | US | disclosed |
| US-9403849-B2 | Organic electroluminescent device and boric acid and borinic acid derivatives used therein | MERCK PATENT GMBH (DE) | 2016-08-02 | — | — | US | disclosed |
| US-9403849-B2 | Organic electroluminescent device and boric acid and borinic acid derivatives used therein | MERCK PATENT GMBH (DE) | 2016-08-02 | — | — | US | disclosed |
| US-8674141-B2 | Organic electroluminescent device and boric acid and borinic acid derivatives used therein | MERCK PATENT GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-8124249-B2 | Derivatives of fused aromatic systems; stability; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers | MERCK PATENT GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8124249-B2 | Derivatives of fused aromatic systems; stability; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers | MERCK PATENT GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8124249-B2 | Derivatives of fused aromatic systems; stability; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers | MERCK PATENT GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-20090134384-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND BORIC ACID AND BORINIC ACID DERIVATIVES USED THEREIN | MERCK PATENT GMBH (DE) | 2009-05-28 | — | — | US | disclosed |
| US-20090134384-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND BORIC ACID AND BORINIC ACID DERIVATIVES USED THEREIN | MERCK PATENT GMBH (DE) | 2009-05-28 | — | — | US | disclosed |
| US-20090134384-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND BORIC ACID AND BORINIC ACID DERIVATIVES USED THEREIN | MERCK PATENT GMBH (DE) | 2009-05-28 | — | — | US | disclosed |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090134384-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND BORIC ACID AND BORINIC ACID DERIVATIVES USED THEREIN | BTD, ERG, OR10J3 | ALDH1A1 857/4885MAPK1 738/4885POLB 2799/4885 |
| US-20160322570-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | OR10J3, BTD, ERG | ALDH1A1 1034/4885MAPK1 1444/4885POLB 2138/4885 |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | OR10J3, EML4, TYR | ALDH1A1 1325/4885MAPK1 3925/4885POLB 3323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.