Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.41 |
| ▸ | DRD4 | P21917 | 10/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021982 | 0.88 | TPSAB1 (0.45) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7023789 | 0.85 | TPSAB1 (0.48) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7023793 | 0.83 | F2 (0.42) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7015961 | 0.82 | TPSAB1 (0.40) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL8205180 | 0.81 | TPSAB1 (0.52) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7023919 | 0.80 | TPSAB1 (0.47) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7694668 | 0.80 | TPSAB1 (0.47) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7021913 | 0.79 | F2 (0.42) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7019224 | 0.79 | TPSAB1 (0.42) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7027708 | 0.79 | TPSAB1 (0.43) | TPSAB1F2F7F3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |