Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 7/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023919 | 1.00 | TPSAB1 (0.47) | TPSAB1GRIN2BCYP2D6CYP2C9F2 | |
| SCHEMBL7020166 | 0.91 | TPSAB1 (0.45) | TPSAB1GRIN2BCYP2D6CYP2C9 | |
| SCHEMBL8205180 | 0.88 | TPSAB1 (0.52) | TPSAB1GRIN2BCYP2D6CYP2C9F2 | |
| SCHEMBL7020326 | 0.83 | TPSAB1 (0.43) | TPSAB1F2PRSS1F7F3 | |
| SCHEMBL7027708 | 0.83 | TPSAB1 (0.43) | TPSAB1F2PRSS1F7F3 | |
| SCHEMBL7403728 | 0.83 | TPSAB1 (0.49) | TPSAB1F2PRSS1F7F3 | |
| SCHEMBL7020466 | 0.81 | TPSAB1 (0.43) | TPSAB1F2PRSS1F7F3 | |
| SCHEMBL7029085 | 0.81 | TPSAB1 (0.43) | TPSAB1F2PRSS1F7F3 | |
| SCHEMBL7018545 | 0.81 | TPSAB1 (0.43) | TPSAB1F2PRSS1F7F3 | |
| SCHEMBL7021799 | 0.81 | TPSAB1 (0.43) | TPSAB1F2PRSS1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |