SCHEMBL7016070

SCHEMBL7016070

CC(=O)CCC(=O)CC(C)=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.70
KDM6B O15054 1/20 0.70
KDM5C P41229 1/20 0.70
EGLN1 Q9GZT9 1/20 0.70
PHF8 Q9UPP1 1/20 0.70
KDM2A Q9Y2K7 1/20 0.70
ALDH1A1 P00352 4/20 0.62
LMNA P02545 2/20 0.50
SLC15A2 Q16348 1/20 0.50
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
HTT P42858 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
PAOX Q6QHF9 3/20 0.36
ACHE P22303 1/20 0.36
TRPA1 O75762 1/20 0.35
GABRR1 P24046 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61062 0.94 KDM4E (0.78) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL21044870 0.90 ALDH1A1 (0.67) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL8155389 0.83 ALDH1A1 (0.77) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL10662938 0.83 ALDH1A1 (0.77) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL2439884 0.83 ALDH1A1 (0.77) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL1683265 0.82 KDM4E (0.56) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL10836799 0.82 ALDH1A1 (0.56) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL1172512 0.82 EGLN1 (0.64) KDM4EKDM6BKDM5CEGLN1PHF8
Succinylacetone SCHEMBL503918 0.82 PHF8 (1.00) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL8846311 0.81 KDM4E (0.62) KDM4EKDM6BKDM5CEGLN1PHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4006063-A1 METHOD FOR PRODUCING FLUOROPOLYMER, POLYTETRAFLUOROETHYLENE COMPOSITION, AND POLYTETRAFLUOROETHYLENE POWDER Daikin Industries, Ltd. (JP) 2022-06-01 EP disclosed
EP-3919527-A1 METHOD FOR PRODUCING POLYTETRAFLUOROETHYLENE DAIKIN INDUSTRIES, LTD. (JP) 2021-12-08 EP disclosed
EP-2735581-B1 COMPOSITION AND POLYMER ASAHI CHEMICAL IND (JP) 2021-07-14 EP disclosed
EP-3666802-A1 METHOD FOR PRODUCING PURIFIED POLYTETRAFLUOROETHYLENE AQUEOUS DISPERSION LIQUID, METHOD FOR PRODUCING MODIFIED POLYTETRAFLUOROETHYLENE POWDER, METHOD FOR PRODUCING POLYTETRAFLUOROETHYLENE MOLDED BODY, AND COMPOSITION Daikin Industries, Ltd. (JP) 2020-06-17 EP disclosed
US-9738757-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-08-22 US disclosed
US-9714328-B2 Sugar chain-capturing substance and use thereof SUMITOMO BAKELITE COMPANY, LTD. (JP) 2017-07-25 US disclosed
US-20160327568-A1 COMPOSITION, METHOD FOR PREPARING SUGAR CHAIN SAMPLE, AND METHOD FOR ANALYZING SUGAR CHAIN SUMITOMO BAKELITE CO., LTD. (JP) 2016-11-10 US disclosed
US-20160222168-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-08-04 US disclosed
US-9376594-B2 Polishing composition FUJIMI INCORPORATED (JP) 2016-06-28 US disclosed
US-9334371-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-05-10 US disclosed
US-20150069016-A1 POLISHING COMPOSITION FUJIMI INCORPORATED (JP) 2015-03-12 US disclosed
EP-2735581-A1 COMPOSITION AND POLYMER Asahi Kasei Chemicals Corporation (JP) 2014-05-28 EP disclosed
US-20140121293-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-05-01 US disclosed
EP-0989978-B1 TRICYCLIC KETO AMIDE DERIVATIVES USEFUL AS FARNESYL PROTEIN TRANSFERASE INHIBITORS SCHERING CORP (US) 2007-03-14 EP disclosed
EP-1307455-A2 INHIBITORS OF ALPHA-L BETA-2 MEDIATED CELL ADHESION TANABE SEIYAKU CO., LTD. (JP) 2003-05-07 EP disclosed
WO-2001030781-A2 INHIBITORS OF αLβ2 MEDIATED CELL ADHESION TANABE SEIYAKU CO., LTD. (JP) 2001-05-03 WO disclosed