Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013129 | 0.90 | ALDH1A1 (0.65) | ALDH1A1USP2NPSR1NPC1RAB9A | |
| SCHEMBL7014792 | 0.90 | ALDH1A1 (0.74) | ALDH1A1NPSR1NPC1RAB9AMEN1 | |
| SCHEMBL7020221 | 0.89 | ALDH1A1 (0.63) | ALDH1A1USP2NPSR1NPC1RAB9A | |
| SCHEMBL7020310 | 0.88 | ALDH1A1 (0.57) | ALDH1A1NPSR1NPC1RAB9AKMT2A | |
| SCHEMBL7023964 | 0.88 | ALDH1A1 (0.65) | ALDH1A1NPSR1NPC1RAB9AMEN1 | |
| SCHEMBL7023261 | 0.87 | ALDH1A1 (0.70) | ALDH1A1NPSR1NPC1RAB9AMEN1 | |
| SCHEMBL7021872 | 0.87 | ALDH1A1 (0.58) | ALDH1A1NPSR1NPC1RAB9AMEN1 | |
| SCHEMBL7020235 | 0.87 | ALDH1A1 (0.58) | ALDH1A1NPSR1NPC1RAB9AKMT2A | |
| SCHEMBL7016915 | 0.86 | ALDH1A1 (0.57) | ALDH1A1NPSR1NPC1RAB9AKMT2A | |
| SCHEMBL7018437 | 0.86 | ALDH1A1 (0.57) | ALDH1A1NPSR1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |