Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | JUN | P05412 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011306 | 0.85 | TRPV1 (0.45) | SLC13A3MEN1KMT2ALMNAMGLL | |
| SCHEMBL5115340 | 0.82 | KDM4E (0.46) | SLC13A3LMNAMAPK1RAB9AMAPT | |
| SCHEMBL7012969 | 0.82 | MEN1 (0.45) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL7019146 | 0.82 | MEN1 (0.45) | MEN1KMT2AMAPK1RAB9ATGM2 | |
| SCHEMBL7011472 | 0.81 | MEN1 (0.56) | SLC13A3MEN1KMT2AMAPK1RAB9A | |
| SCHEMBL7017825 | 0.80 | MEN1 (0.45) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL7021855 | 0.79 | SMN1; SMN2 (0.47) | SLC13A3LMNAMAPK1MAPT | |
| SCHEMBL7020642 | 0.78 | MEN1 (0.44) | MEN1KMT2AMAPK1RAB9AMGLL | |
| SCHEMBL7016001 | 0.78 | MGLL (0.52) | SLC13A3MEN1KMT2ARAB9AMGLL | |
| SCHEMBL7014110 | 0.77 | MEN1 (0.43) | MEN1KMT2ALMNAMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |