Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5115340 | 0.85 | KDM4E (0.46) | SMN1; SMN2SLC13A3LMNAALDH1A1HTT | |
| SCHEMBL7014986 | 0.83 | LMNA (0.52) | SMN1; SMN2LMNAALDH1A1TSHRHTT | |
| SCHEMBL7015250 | 0.81 | TSHR (0.55) | SMN1; SMN2LMNAALDH1A1TSHRHTT | |
| SCHEMBL7018531 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAALDH1A1TSHRHTT | |
| SCHEMBL7011306 | 0.80 | TRPV1 (0.45) | SMN1; SMN2SLC13A3LMNAALDH1A1L3MBTL1 | |
| SCHEMBL7016497 | 0.79 | SLC13A3 (0.42) | SLC13A3LMNAMAPK1MAPT | |
| SCHEMBL7014547 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAALDH1A1TSHRHTT | |
| SCHEMBL7016543 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAALDH1A1TSHRHTT | |
| SCHEMBL7016001 | 0.78 | MGLL (0.52) | SMN1; SMN2SLC13A3ALDH1A1TSHRMAOB | |
| SCHEMBL686791 | 0.78 | RXFP1 (0.48) | SMN1; SMN2SLC13A3LMNAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |