Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016674 | 0.96 | PTPN12 (0.47) | CNR1CNR2GPR55MAPTHTT | |
| SCHEMBL7015240 | 0.91 | PDE4A (0.45) | CNR1CNR2GPR55MAPTHTT | |
| SCHEMBL8184822 | 0.90 | PDE4A (0.45) | CNR1CNR2GPR55MAPTHTT | |
| SCHEMBL7013403 | 0.89 | MAPT (0.45) | CNR1GPR55MAPTHTTSMN1; SMN2 | |
| SCHEMBL7013985 | 0.89 | PTPN12 (0.43) | CNR1CNR2GPR55MAPTHTT | |
| SCHEMBL7011351 | 0.88 | PDE4A (0.42) | MAPTHTTSMN1; SMN2NPSR1MEN1 | |
| SCHEMBL7022055 | 0.88 | SMN1; SMN2 (0.49) | CNR1GPR55MAPTHTTSMN1; SMN2 | |
| SCHEMBL7019969 | 0.88 | MEN1 (0.49) | CNR1GPR55MAPTHTTSMN1; SMN2 | |
| SCHEMBL7020386 | 0.87 | MAPT (0.44) | CNR1GPR55MAPTHTTSMN1; SMN2 | |
| SCHEMBL7018811 | 0.87 | PDE4A (0.45) | MAPTNPSR1MEN1KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934321-B1 | THIENOPYRIMIDINE WITH PHOSPHODIESTERASE V INHIBITING EFFECT | MERCK PATENT GMBH (DE) | 2003-08-06 | — | — | EP | disclosed |