Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7022055 | 0.94 | SMN1; SMN2 (0.49) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL7009771 | 0.90 | PDE5A (0.50) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL7013403 | 0.89 | MAPT (0.45) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL8181825 | 0.89 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL7020386 | 0.89 | MAPT (0.44) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL7014106 | 0.89 | HTT (0.41) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL7016750 | 0.88 | CNR1 (0.46) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL7016674 | 0.88 | PTPN12 (0.47) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL7011555 | 0.87 | PDE5A (0.44) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL7012439 | 0.86 | ALDH1A1 (0.43) | MEN1KMT2ASMN1; SMN2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934321-B1 | THIENOPYRIMIDINE WITH PHOSPHODIESTERASE V INHIBITING EFFECT | MERCK PATENT GMBH (DE) | 2003-08-06 | — | — | EP | disclosed |