Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015455 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPK1HSD17B10SQORSMN1; SMN2 | |
| SCHEMBL7011446 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPK1HSD17B10SQORSMN1; SMN2 | |
| SCHEMBL7021596 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPK1HSD17B10SQORSMN1; SMN2 | |
| SCHEMBL7022639 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPK1HSD17B10SQORSMN1; SMN2 | |
| SCHEMBL7018816 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPK1HSD17B10SQORSMN1; SMN2 | |
| SCHEMBL7013301 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPK1HSD17B10SQORSMN1; SMN2 | |
| SCHEMBL7021434 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPK1HSD17B10SQORSMN1; SMN2 | |
| SCHEMBL7021502 | 0.82 | RAB9A (0.44) | ALDH1A1MAPK1HSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL7021810 | 0.82 | KISS1R (0.49) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL7015533 | 0.82 | KISS1R (0.47) | ALDH1A1MAPK1HSD17B10SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1441783-A | Drug containing dicyanopyridine derivative | YAMANOUCHI PHARMA CO LTD (JP) | 2003-09-10 | — | — | CN | disclosed |
| EP-1302463-A1 | MEDICINE COMPRISING DICYANOPYRIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-04-16 | — | — | EP | disclosed |