Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.36 |
| ▸ | JAK1 | P23458 | 3/20 | 0.36 |
| ▸ | JAK3 | P52333 | 3/20 | 0.36 |
| ▸ | NPY1R | P25929 | 11/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018069 | 0.75 | HTR2C (0.31) | — | |
| SCHEMBL113716 | 0.74 | KCNH2 (0.41) | NPY1RPIK3CAKCNH2 | |
| SCHEMBL7011740 | 0.74 | CASR (0.36) | JAK2JAK1JAK3NPY1RKCNH2 | |
| SCHEMBL7016776 | 0.73 | CASR (0.35) | NPY1RKCNH2 | |
| SCHEMBL7012036 | 0.73 | ZAP70 (0.32) | — | |
| SCHEMBL7017580 | 0.72 | NPY1R (0.37) | NPY1RKCNH2 | |
| SCHEMBL7012953 | 0.72 | AOC3 (0.36) | — | |
| SCHEMBL7012955 | 0.70 | KCNH2 (0.35) | NPY1RKCNH2 | |
| SCHEMBL167647 | 0.70 | HTR2C (0.35) | NPY1RPIK3CB | |
| SCHEMBL113428 | 0.70 | KCNH2 (0.36) | NPY1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |