Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL337857 | 0.83 | L3MBTL1 (0.68) | L3MBTL1HCAR3WNK1MAPTTDP1 | |
| SCHEMBL15984934 | 0.81 | EGFR (0.55) | L3MBTL1HCAR3WNK1MAPTTDP1 | |
| SCHEMBL7018311 | 0.81 | ALDH3A1 (0.58) | L3MBTL1HCAR3WNK1MAPTTDP1 | |
| SCHEMBL11381627 | 0.79 | IDO1 (0.58) | L3MBTL1HCAR3WNK1MAPTTDP1 | |
| SCHEMBL27697298 | 0.78 | EGFR (0.48) | L3MBTL1HCAR3WNK1MAPTTDP1 | |
| SCHEMBL3323396 | 0.77 | MAPT (0.51) | L3MBTL1HCAR3WNK1MAPTTDP1 | |
| SCHEMBL14316100 | 0.76 | ALDH1A1 (0.55) | L3MBTL1HCAR3WNK1MAPTTDP1 | |
| SCHEMBL6383792 | 0.76 | GAA (0.42) | L3MBTL1MAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL7100350 | 0.75 | MAPT (0.43) | L3MBTL1HCAR3MAPTTDP1POLB | |
| SCHEMBL6427804 | 0.75 | MAPT (0.44) | L3MBTL1HCAR3WNK1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326864-A2 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-1326606-A2 | EP4 RECEPTOR INHIBITORS TO TREAT RHEUMATOID ARTHRITIS | PFIZER PHARMACEUTICALS INC. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032422-A2 | EP4 RECEPTOR INHIBITORS TO TREAT RHEUMATOID ARTHRITIS | PFIZER PHARMACEUTICALS INC. (JP) | 2002-04-25 | — | — | WO | disclosed |
| WO-2002032900-A2 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 2002-04-25 | — | — | WO | disclosed |