SCHEMBL7017288

SCHEMBL7017288

CS(=O)(=O)Nc1cc(N=C=O)c(F)cc1Cl

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NEU3 Q9UQ49 1/20 0.35
PPOX P50336 1/20 0.35
MAPT P10636 1/20 0.34
MAOB P27338 1/20 0.34
PIK3CD O00329 2/20 0.32
PIK3CA P42336 2/20 0.32
PIK3CB P42338 2/20 0.32
PIK3CG P48736 2/20 0.32
GLO1 Q04760 1/20 0.32
CCR2 P41597 1/20 0.31
NR3C1 P04150 1/20 0.31
PGR P06401 1/20 0.31
NR3C2 P08235 1/20 0.31
AR P10275 1/20 0.31
DRD2 P14416 1/20 0.31
DRD3 P35462 1/20 0.31
KDM1A O60341 1/20 0.31
MAOA P21397 1/20 0.31
EGFR P00533 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6199133 0.83 KMT2A (0.34)
SCHEMBL7566023 0.81
SCHEMBL7931545 0.75 TDP1 (0.45)
SCHEMBL10347965 0.73 TDP1 (0.39) KDM1A
SCHEMBL10519626 0.73 PSIP1 (0.41) PIK3CDPIK3CAPIK3CBPIK3CGPGR
SCHEMBL9836795 0.73 CYP3A4 (0.42)
SCHEMBL13687162 0.70 MAPT (0.43) MAPT
SCHEMBL31118323 0.70 BRD4 (0.39) PPOXMAPT
SCHEMBL3528197 0.70 CCR2 (0.44) NEU3MAPTCCR2
SCHEMBL11603971 0.69 MCL1 (0.50) PPOXMAOBPIK3CDPIK3CAPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0862571-B1 HERBICIDAL SULFONAMIDES DEGUSSA (DE) 2003-01-15 EP disclosed
EP-0863142-A1 Heterocyclic herbicides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-09-09 EP disclosed