Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020110 | 0.85 | POLB (0.36) | POLBSMN1; SMN2PDK2AOC3ABCG2 | |
| SCHEMBL7015622 | 0.80 | PBRM1 (0.41) | POLBSMN1; SMN2PDK2AOC3ABCG2 | |
| SCHEMBL27357705 | 0.76 | POLB (0.38) | POLBSMN1; SMN2PDK2AOC3ABCG2 | |
| SCHEMBL8596999 | 0.76 | POLB (0.38) | POLBSMN1; SMN2PDK2AOC3ABCG2 | |
| SCHEMBL7020959 | 0.76 | POLB (0.36) | POLBSMN1; SMN2PDK2AOC3ABCG2 | |
| SCHEMBL9131392 | 0.75 | POLB (0.38) | POLBSMN1; SMN2PDK2AOC3ABCG2 | |
| SCHEMBL9257119 | 0.74 | POLB (0.40) | POLBSMN1; SMN2PDK2AOC3ABCG2 | |
| SCHEMBL8788397 | 0.74 | NPSR1 (0.55) | SMN1; SMN2ABCG2NPC1RAB9AHPGD | |
| SCHEMBL9430611 | 0.73 | ABCG2 (0.45) | POLBSMN1; SMN2AOC3ABCG2NPC1 | |
| SCHEMBL6188044 | 0.73 | GRM5 (0.39) | POLBSMN1; SMN2AOC3ABCG2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846117-B1 | PROCESS FOR PREPARATION OF BIPHENYL DERIVATIVES | WYETH CORP (US) | 2003-05-14 | — | — | EP | claimed |
| EP-0846117-A1 | PROCESS FOR PREPARATION OF BIPHENYL DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-10 | — | — | EP | claimed |
| US-5760220-A | REACTING PROTECTED TETRAZOLYLPHENYL ZINC HALIDE WITH HALOPHENYLMETHYL PYRIDO/2,3-D/PYRIMIDONE IN PRESENCE OF PALLADIUM OR NICKEL CATALYST | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-02 | — | — | US | claimed |
| WO-1996040684-A1 | PROCESS FOR PREPARATION OF BIPHENYL DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-12-19 | — | — | WO | claimed |
| EP-0846117-B1 | PROCESS FOR PREPARATION OF BIPHENYL DERIVATIVES | WYETH CORP (US) | 2003-05-14 | — | — | EP | disclosed |
| US-5977372-A | Chloro or bromo[2-[2-(tert-butyl)-2H-tetrazol-5-yl]phenyl]zinc intermediates | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| US-5977372-A | Chloro or bromo[2-[2-(tert-butyl)-2H-tetrazol-5-yl]phenyl]zinc intermediates | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0846117-A1 | PROCESS FOR PREPARATION OF BIPHENYL DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5760220-A | REACTING PROTECTED TETRAZOLYLPHENYL ZINC HALIDE WITH HALOPHENYLMETHYL PYRIDO/2,3-D/PYRIMIDONE IN PRESENCE OF PALLADIUM OR NICKEL CATALYST | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |
| WO-1996040684-A1 | PROCESS FOR PREPARATION OF BIPHENYL DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |